Oxidative Stress to Promote Cell Death or Survival
نویسندگان
چکیده
1Department of Earth, Life and Environmental Sciences, University of Urbino Carlo Bo, Campus Scientifico “E. Mattei”, Via Ca’ le Suore 2, 61029 Urbino, Italy 2Department of Neurological and Movement Sciences, Anatomy and Histology Section, University of Verona, Strada le Grazie 8, 37134 Verona, Italy 3Department of Technology and Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
منابع مشابه
بررسی اثر نوروپروتکتیو آدنوزین بر بقای سلول‌های بنیادی عصبی در شرایط آسیب اکسیداتیو با پراکسید هیدروژن
Background and Objective: Excessive production of free radicals during oxidative stress can cause serious damage to important biomolecules and activate programmed cell death pathways in the body. In the nervous system, neuronal cell death leads to many progressive neurodegenerative disorders. The aim of this study was to evaluate the effects of adenosine on the inhibition of apoptosis in oxidat...
متن کاملنقش استرس اکسیداتیو در تکثیر بی‌رویه و مرگ سلولی
Abstract During normal cellular activities Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) are produced. In addition to beneficial functions they play a critical role in cell death and prevent apoptosis. Every cell is equipped with an extensive antioxidant defense system to combat the excessive production of active radicals. Oxidative stress occurs with destruction of cellu...
متن کاملCell Survival Effects of Autophagy Regulation on Umbilical Cord-Derived Mesenchymal Stem Cells Following Exposure to Oxidative Stress
Background: Due to oxidative stress, hypoxia, and serum deprivation, a large percentage of mesenchymal stem cells (MSCs) die in the early stages of transplantation. The present study aimed to address whether induction or inhibition of autophagy would affect the viability of MSCs after exposure to oxidative stress.Methods: MSCs were isolated from umbilical cord tissue using the Ficoll grad...
متن کاملتأثیر آنتی-آپوپتوتیک سلژلین به‌عنوان بازدارنده‌ی مونو آمین اکسیداز بر سلول‌های بنیادی عصبی مشتق شده از هیپوکمپ موش صحرایی در شرایط آسیب اکسیداتیو
Background and Objective: Damaged and inflammatory cells in the nervous system produce reactive oxygen species (ROS). The overproduction of ROS can cause serious damage to important biomolecules and over activation of programmed cell death leads to many progressive neurodegenerative disorders. The aim of this study was to evaluate the effects of selegiline on inhibition of apoptosis in oxidativ...
متن کاملSituations Leading to Oxidative Stress in Dairy Cattle
Free radicals are normally produced by living organism, at controlled production rate they perform physiological functions as signal transduction molecules. However, situations leading to an overproduction that surpasses antioxidant capacity creates oxidative stress. Consequently, damage to the cell membrane, protein, DNA and cell death are observed. Dairy cattle are susceptible to oxidative st...
متن کاملRole of Oxidative Stress in Modulating Unfolded Protein Response Activity in Chronic Myeloid Leukemia Cell Line
Background: Recently, it has been revealed that tyrosine kinase inhibitors (TKIs) act through inducing both oxidative and endoplasmic reticulum (ER) stress in chronic myeloid leukemia cells. However, ER stress signaling triggers both apoptotic and survival processes within cells. Nevertheless, mechanisms by which TKIs avoid the pro-survival effects are not clear. The aim of this study was to ev...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016